articleEuropean Journal of PainMar 30, 2005BRONZE OA

Quantitative sensory testing: a comprehensive protocol for clinical trials

Johannes Gutenberg University Mainz · University College London

PubMed
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Abstract

We have compiled a comprehensive QST protocol as part of the German Research Network on Neuropathic Pain (DFNS) using well established tests for nearly all aspects of somatosensation. This protocol encompasses thermal as well as mechanical testing procedures. Our rationale was to test for patterns of sensory loss (small and large nerve fiber functions) or gain (hyperalgesia, allodynia, hyperpathia), and to assess both cutaneous and deep pain sensitivity. The practicality of the QST protocol was tested in 18 healthy subjects, 21-58 years, half of them female. All subjects were tested bilaterally over face, hand and foot. We determined thermal detection and pain thresholds including a test for the presence of…

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Authors

7

Topics & keywords

Keywords
  • Allodynia
  • Quantitative sensory testing
  • Audiology
  • Medicine
  • Neuropathic pain
  • Sensory system
  • Stimulus (psychology)
  • Physical medicine and rehabilitation
UN Sustainable Development Goals
  • Good health and well-being
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