articleJournal of Animal Breeding and GeneticsJul 11, 2006Closed access

Strategy for applying genome‐wide selection in dairy cattle

University of Guelph

PubMed
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Abstract

Animals can be genotyped for thousands of single nucleotide polymorphisms (SNPs) at one time, where the SNPs are located at roughly 1-cM intervals throughout the genome. For each contiguous pair of SNPs there are four possible haplotypes that could be inherited from the sire. The effects of each interval on a trait can be estimated for all intervals simultaneously in a model where interval effects are random factors. Given the estimated effects of each haplotype for every interval in the genome, and given an animal's genotype, a 'genomic' estimated breeding value is obtained by summing the estimated effects for that genotype. The accuracy of that estimator of breeding values is around 80%. Because the genomic…

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Topics & keywords

Keywords
  • Sire
  • Selection (genetic algorithm)
  • Haplotype
  • Biology
  • Single-nucleotide polymorphism
  • Genome
  • Genetics
  • Livestock
UN Sustainable Development Goals
  • Zero hunger
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