reviewCurrent Cancer Drug TargetsOct 30, 2008GREEN OA

Luteolin, a Flavonoid with Potential for Cancer Prevention and Therapy

Lovelace Respiratory Research Institute

PubMed
Indexed incrossrefpubmed

Abstract

Luteolin, 3',4',5,7-tetrahydroxyflavone, is a common flavonoid that exists in many types of plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and cancer. Having multiple biological effects such as anti-inflammation, anti-allergy and anticancer, luteolin functions as either an antioxidant or a pro-oxidant biochemically. The biological effects of luteolin could be functionally related to each other. For instance, the anti-inflammatory activity may be linked to its anticancer property. Luteolin's anticancer property is associated with the induction of…

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1,157
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7.02
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100%
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Authors

4

Topics & keywords

Keywords
  • Luteolin
  • Fisetin
  • Pharmacology
  • Cancer research
  • PI3K/AKT/mTOR pathway
  • XIAP
  • Cancer
  • Cancer cell
UN Sustainable Development Goals
  • Good health and well-being
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