articleThe Plant CellApr 14, 2006BRONZE OA

Functional Analysis of an Arabidopsis Transcription Factor, DREB2A, Involved in Drought-Responsive Gene Expression

YSYoh SakumaKMKyonoshin MaruyamaYOYuriko OsakabeFQFeng QinMSMotoaki Seki

Japan International Research Center for Agricultural Sciences · Center for Genomic Science · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Transcription factors DREB1A/CBF3 and DREB2A specifically interact with cis-acting dehydration-responsive element/C-repeat (DRE/CRT) involved in cold and drought stress-responsive gene expression in Arabidopsis thaliana. Intact DREB2A expression does not activate downstream genes under normal growth conditions, suggesting that DREB2A requires posttranslational modification for activation, but the activation mechanism has not been clarified. DREB2A domain analysis using Arabidopsis protoplasts identified a transcriptional activation domain between residues 254 and 335, and deletion of a region between residues 136 and 165 transforms DREB2A to a constitutive active form. Overexpression of constitutive active…

Citation impact

1,146
total citations
FWCI
53.25
Percentile
100%
References
43
Citations per year

Authors

7

Topics & keywords

Topics
Keywords
  • Biology
  • Arabidopsis
  • Gene
  • Gene expression
  • Arabidopsis thaliana
  • Transcription factor
  • Cell biology
  • Microarray analysis techniques
UN Sustainable Development Goals
  • Clean water and sanitation
No related works found for this paper.

Funding