A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression
National Institute of Mental Health · National Institute of Mental Health
Indexed incrossrefpubmed
Abstract
Objective
To determine whether a rapid antidepressant effect can be achieved with an antagonist at the N-methyl-D-aspartate receptor in subjects with major depression.
Design
A randomized, placebo-controlled, double-blind crossover study from November 2004 to September 2005.
Citation impact
3,739
total citations
- FWCI
- 56.30
- Percentile
- 100%
- References
- 65
Citations per year
Authors
8- CACarlos A. ZarateCorresponding
National Institute of Mental Health, National Institute of Mental Health
- JSJaskaran Singh
National Institute of Mental Health, National Institute of Mental Health
- PJPaul J. Carlson
National Institute of Mental Health, National Institute of Mental Health
- NENancy E. Brutsché
National Institute of Mental Health, National Institute of Mental Health
- RARezvan Ameli
National Institute of Mental Health, National Institute of Mental Health
Topics & keywords
Topics
Keywords
- Placebo
- Randomized controlled trial
- Depression (economics)
- Mood
- Ketamine hydrochloride
- Medicine
- Antidepressant
- Confidence interval
UN Sustainable Development Goals
- Good health and well-being
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