Sensitivity and Specificity of a Single Emergency Department Measurement of Urinary Neutrophil Gelatinase–Associated Lipocalin for Diagnosing Acute Kidney Injury

Nickolas, Thomas L.; O’Rourke, Matthew; Yang, Jun; Sise, Meghan E.; Canetta, Pietro A.; Barasch, Nicholas; Buchen, Charles; Khan, Faris; Mori, Kiyoshi; Giglio, James; Devarajan, Prasad; Barasch, Jonathan

doi:10.7326/0003-4819-148-11-200806030-00003

articleAnnals of Internal MedicineJun 3, 2008GREEN OA

Sensitivity and Specificity of a Single Emergency Department Measurement of Urinary Neutrophil Gelatinase–Associated Lipocalin for Diagnosing Acute Kidney Injury

TLThomas L. Nickolas MOMatthew O’Rourke JYJun Yang MEMeghan E. Sise PAPietro A. Canetta

University of Cincinnati Medical Center

PubMed

Indexed incrossrefpubmed

Abstract

Background

A single serum creatinine measurement cannot distinguish acute kidney injury from chronic kidney disease or prerenal azotemia.

Objective

To test the sensitivity and specificity of a single measurement of urinary neutrophil gelatinase-associated lipocalin (NGAL) and other urinary proteins to detect acute kidney injury in a spectrum of patients.

Citation impact

679

total citations

FWCI: 34.06
Percentile: 100%
References: 52

Citations per year

Authors

12

Topics & keywords

Topics

Keywords

Medicine
Acute kidney injury
Creatinine
Kidney disease
Urinary system
Renal function
Internal medicine
Azotemia

UN Sustainable Development Goals

Good health and well-being

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