Critical assessment of methods of protein structure prediction (CASP) — round x

This article is an introduction to the special issue of the journal PROTEINS, dedicated to the tenth Critical Assessment of Structure Prediction (CASP) experiment to assess the state of the art in protein structure modeling. The article describes the conduct of the experiment, the categories of prediction included, and outlines the evaluation and assessment procedures. The 10 CASP experiments span almost 20 years of progress in the field of protein structure modeling, and there have been enormous advances in methods and model accuracy in that period. Notable in this round is the first sustained improvement of models with refinement methods, using molecular dynamics. For the first time, we tested the ability of…

• KA
  King Abdullah University of Science and Technology

  Award: KUK-I1-012-43
• NI
  National Institutes of Health

  Award: R01GM100482
• NI
  National Institute of General Medical Sciences

  Award: R01GM100482