Gut Microbiota in Health and Disease
University of British Columbia · Canada's Michael Smith Genome Sciences Centre
Abstract
Gut microbiota is an assortment of microorganisms inhabiting the length and width of the mammalian gastrointestinal tract. The composition of this microbial community is host specific, evolving throughout an individual's lifetime and susceptible to both exogenous and endogenous modifications. Recent renewed interest in the structure and function of this "organ" has illuminated its central position in health and disease. The microbiota is intimately involved in numerous aspects of normal host physiology, from nutritional status to behavior and stress response. Additionally, they can be a central or a contributing cause of many diseases, affecting both near and far organ systems. The overall balance in the…
Citation impact
- FWCI
- 55.26
- Percentile
- 100%
- References
- 358
Authors
4- ISInna SekirovCorresponding
University of British Columbia, Canada's Michael Smith Genome Sciences Centre
- SRShannon Russell
University of British Columbia, Canada's Michael Smith Genome Sciences Centre
- LCL. Caetano M. Antunes
University of British Columbia, Canada's Michael Smith Genome Sciences Centre
- BBB. Brett Finlay
University of British Columbia, Canada's Michael Smith Genome Sciences Centre
Topics & keywords
- Gut flora
- Disease
- Biology
- Immune system
- Gastrointestinal tract
- Immunology
- Dysbiosis
- Homeostasis
- Zero hunger