articleCurrent Protocols in ImmunologyNov 1, 2015Closed access

Trypan Blue Exclusion Test of Cell Viability

National Institute of Allergy and Infectious Diseases

PubMed
Indexed incrossrefpubmed

Abstract

The protocol described in this appendix allows for light microscopic quantitation of cell viability. Cells are suspended in PBS containing trypan blue and then examined to determine the percentage of cells that have clear cytoplasm (viable cells) versus cells that have blue cytoplasm (nonviable cells).

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Topics & keywords

Keywords
  • Trypan blue
  • Cytoplasm
  • Viability assay
  • Cell
  • Molecular biology
  • Cell counting
  • Biology
  • Cell biology
UN Sustainable Development Goals
  • Reduced inequalities
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