SAbDab: the structural antibody database
University of Oxford · Roche (United Kingdom) · +1 more institution
Abstract
Structural antibody database (SAbDab; http://opig.stats.ox.ac.uk/webapps/sabdab) is an online resource containing all the publicly available antibody structures annotated and presented in a consistent fashion. The data are annotated with several properties including experimental information, gene details, correct heavy and light chain pairings, antigen details and, where available, antibody-antigen binding affinity. The user can select structures, according to these attributes as well as structural properties such as complementarity determining region loop conformation and variable domain orientation. Individual structures, datasets and the complete database can be downloaded.
Citation impact
- FWCI
- 10.59
- Percentile
- 100%
- References
- 39
Authors
8- JBJames B. DunbarCorresponding
- KKKonrad Krawczyk
University of Oxford, Roche (United Kingdom), UCB Pharma (United Kingdom)
- JLJinwoo Leem
UCB Pharma (United Kingdom), University of Oxford, Roche (United Kingdom)
- TBTerry Baker
UCB Pharma (United Kingdom), University of Oxford, Roche (United Kingdom)
- AFAngelika Fuchs
UCB Pharma (United Kingdom), University of Oxford, Roche (United Kingdom)
Topics & keywords
- Biology
- Complementarity determining region
- Complementarity (molecular biology)
- Database
- Antibody
- Computational biology
- Antigen
- Immunoglobulin light chain