Radical Prostatectomy versus Observation for Localized Prostate Cancer
University of Minnesota · Minneapolis VA Health Care System · +21 more institutions
Abstract
The effectiveness of surgery versus observation for men with localized prostate cancer detected by means of prostate-specific antigen (PSA) testing is not known.
From November 1994 through January 2002, we randomly assigned 731 men with localized prostate cancer (mean age, 67 years; median PSA value, 7.8 ng per milliliter) to radical prostatectomy or observation and followed them through January 2010. The primary outcome was all-cause mortality; the secondary outcome was prostate-cancer mortality.
Citation impact
- FWCI
- 189.68
- Percentile
- 100%
- References
- 44
Authors
21- TJTimothy J WiltCorresponding
University of Minnesota, Minneapolis VA Health Care System
- MKMichael K. Brawer
Innovative Designs in Environments for an Aging Society
- KJKaren Jones
Program Support Center
- MJMichael J. Barry
Massachusetts General Hospital
- WJWilliam J. Aronson
VA Greater Los Angeles Healthcare System
Topics & keywords
- Medicine
- Prostatectomy
- Prostate cancer
- Hazard ratio
- Urology
- Confidence interval
- Prostate
- Prostate-specific antigen
- Good health and well-being