articleFrontiers in NeuroinformaticsJan 1, 2011GOLD OA

Automated probabilistic reconstruction of white-matter pathways in health and disease using an atlas of the underlying anatomy

AYAnastasia Yendiki

Massachusetts General Hospital

PubMed
Indexed incrossrefdoajpubmed

Abstract

We have developed a method for automated probabilistic reconstruction of a set of major white-matter pathways from diffusion-weighted MR images. Our method is called TRACULA (TRActs Constrained by UnderLying Anatomy) and utilizes prior information on the anatomy of the pathways from a set of training subjects. By incorporating this prior knowledge in the reconstruction procedure, our method obviates the need for manual interaction with the tract solutions at a later stage and thus facilitates the application of tractography to large studies. In this paper we illustrate the application of the method on data from a schizophrenia study and investigate whether the inclusion of both patients and healthy subjects in…

Citation impact

628
total citations
FWCI
14.76
Percentile
100%
References
142
Citations per year

Authors

1

Topics & keywords

Topics
Keywords
  • Tractography
  • White matter
  • Computer science
  • Artificial intelligence
  • Set (abstract data type)
  • Diffusion MRI
  • Brain anatomy
  • Probabilistic logic
No related works found for this paper.

Funding