Network Analysis of the MVA and MEP Pathways for Isoprenoid Synthesis
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Abstract
Isoprenoid biosynthesis is essential for all living organisms, and isoprenoids are also of industrial and agricultural interest. All isoprenoids are derived from prenyl diphosphate (prenyl-PP) precursors. Unlike isoprenoid biosynthesis in other living organisms, prenyl-PP, as the precursor of all isoprenoids in plants, is synthesized by two independent pathways: the mevalonate (MVA) pathway in the cytoplasm and the 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway in plastids. This review focuses on progress in our understanding of how the precursors for isoprenoid biosynthesis are synthesized in the two subcellular compartments, how the underlying pathway gene networks are organized and regulated, and how…
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1,134
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Authors
3Topics & keywords
Topics
Keywords
- Prenylation
- Terpenoid
- Biosynthesis
- Plastid
- Mevalonic acid
- Biology
- Biochemistry
- Mevalonate pathway
UN Sustainable Development Goals
- Zero hunger
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