articleBriefings in BioinformaticsMar 27, 2008BRONZE OA

MEGA: A biologist-centric software for evolutionary analysis of DNA and protein sequences

Arizona State University · Pennsylvania State University · +2 more institutions

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Abstract

The Molecular Evolutionary Genetics Analysis (MEGA) software is a desktop application designed for comparative analysis of homologous gene sequences either from multigene families or from different species with a special emphasis on inferring evolutionary relationships and patterns of DNA and protein evolution. In addition to the tools for statistical analysis of data, MEGA provides many convenient facilities for the assembly of sequence data sets from files or web-based repositories, and it includes tools for visual presentation of the results obtained in the form of interactive phylogenetic trees and evolutionary distance matrices. Here we discuss the motivation, design principles and priorities that have…

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Authors

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Topics & keywords

Keywords
  • Mega-
  • Software
  • Phylogenetic tree
  • Set (abstract data type)
  • Computer science
  • DNA sequencing
  • Sequence analysis
  • Data science
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