Facile Discrimination of Aldose Enantiomers by Reversed-Phase HPLC
Nagasaki University · Saga University
Indexed incrossrefpubmed
Abstract
One-pot reactions of aldoses with L-cysteine methyl ester and o-tolyl isothiocyanate yielded methyl 2-(polyhydroxyalkyl)-3-(o-tolylthiocarbamoyl)-thiazolidine-4(R)-carboxylates. Direct HPLC analysis of the reaction mixture and UV detection at 250 nm discriminated D- and L-enantiomers of aldoses. The reaction was applied to the determination of absolute configuration the sugar residues of an aroma precursor.
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5Topics & keywords
Topics
Keywords
- Chemistry
- Enantiomer
- Aldose
- Thiazolidine
- High-performance liquid chromatography
- Chromatography
- Isothiocyanate
- Aroma
UN Sustainable Development Goals
- Reduced inequalities
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