Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
Addenbrooke's Hospital · University of Cambridge · +2 more institutions
Indexed incrossrefpubmed
Abstract
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Citation impact
2,312
total citations
- FWCI
- 26.85
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- 100%
- References
- 49
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Authors
11Topics & keywords
Topics
Keywords
- Autophagy
- Huntingtin
- Huntington's disease
- Neurodegeneration
- PI3K/AKT/mTOR pathway
- Biology
- Huntingtin Protein
- Polyglutamine tract
UN Sustainable Development Goals
- Good health and well-being
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