rehh : an R package to detect footprints of selection in genome-wide SNP data from haplotype structure
Agropolis International · Institut Agro Montpelier · +2 more institutions
Abstract
UNLABELLED: With the development of next-generation sequencing and genotyping approaches, large single nucleotide polymorphism haplotype datasets are becoming available in a growing number of both model and non-model species. Identifying genomic regions with unexpectedly high local haplotype homozygosity relatively to neutral expectation represents a powerful strategy to ascertain candidate genes responding to natural or artificial selection. To facilitate genome-wide scans of selection based on the analysis of long-range haplotypes, we developed the R package rehh. It provides a versatile tool to detect the footprints of recent or ongoing selection with several graphical functions that help visual…
Citation impact
- FWCI
- 16.35
- Percentile
- 100%
- References
- 6
Authors
2Topics & keywords
- R package
- Haplotype
- SNP
- Selection (genetic algorithm)
- Genome
- Computer science
- Computational biology
- Haplotype estimation