Preoperative PSA Velocity and the Risk of Death from Prostate Cancer after Radical Prostatectomy

We evaluated whether men at risk for death from prostate cancer after radical prostatectomy can be identified using information available at diagnosis.

We studied 1095 men with localized prostate cancer to assess whether the rate of rise in the prostate-specific antigen (PSA) level--the PSA velocity--during the year before diagnosis, the PSA level at diagnosis, the Gleason score, and the clinical tumor stage could predict the time to death from prostate cancer and death from any cause after radical prostatectomy.