reviewCritical Reviews in Food Science and NutritionJan 1, 2013Closed access

Protein Oxidation: Basic Principles and Implications for Meat Quality

Iowa State University · Seoul National University · +1 more institution

PubMed
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Abstract

The involvement of oxidized proteins to the development of biological diseases has been studied for a few decades, but the effects and the mechanisms of protein oxidation in food systems are largely unknown. Protein oxidation is defined as the covalent modification of a protein induced either by the direct reactions with reactive oxygen species (ROS) or indirect reactions with secondary by-products of oxidative stress. ROS can cause oxidation in both amino acid side chains and protein backbones, resulting in protein fragmentation or protein-protein cross-linkages. Although all amino acids can be modified by ROS, cysteine, and methionine that are the most susceptible to oxidative changes due to high reaction…

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691
total citations
FWCI
27.21
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100%
References
137
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Authors

3

Topics & keywords

Keywords
  • Chemistry
  • Proteolysis
  • Oxidative stress
  • Oxidative phosphorylation
  • Amino acid
  • Biochemistry
  • Antioxidant
  • Cysteine
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