DEG 10, an update of the database of essential genes that includes both protein-coding genes and noncoding genomic elements: Table 1.
Tianjin University · Wayne State University · +1 more institution
Abstract
The combination of high-density transposon-mediated mutagenesis and high-throughput sequencing has led to significant advancements in research on essential genes, resulting in a dramatic increase in the number of identified prokaryotic essential genes under diverse conditions and a revised essential-gene concept that includes all essential genomic elements, rather than focusing on protein-coding genes only. DEG 10, a new release of the Database of Essential Genes (available at http://www.essentialgene.org), has been developed to accommodate these quantitative and qualitative advancements. In addition to increasing the number of bacterial and archaeal essential genes determined by genome-wide gene essentiality…
Citation impact
- FWCI
- 15.12
- Percentile
- 100%
- References
- 81
Authors
5- HLHao LuoCorresponding
Tianjin University, Wayne State University
- YLYan Lin
Tianjin People's Hospital, Tianjin University, Wayne State University
- FGFeng Gao
Wayne State University, Tianjin University, Tianjin People's Hospital
- CZChun-Ting Zhang
Wayne State University, Tianjin People's Hospital, Tianjin University
- RZRen Zhang
Tianjin University, Wayne State University
Topics & keywords
- Biology
- Gene
- Genetics
- Genome
- Transposable element
- Transposon mutagenesis
- Computational biology
- Genomics