STRING 8--a global view on proteins and their functional interactions in 630 organisms
European Molecular Biology Laboratory · University of Lausanne
Abstract
Functional partnerships between proteins are at the core of complex cellular phenotypes, and the networks formed by interacting proteins provide researchers with crucial scaffolds for modeling, data reduction and annotation. STRING is a database and web resource dedicated to protein-protein interactions, including both physical and functional interactions. It weights and integrates information from numerous sources, including experimental repositories, computational prediction methods and public text collections, thus acting as a meta-database that maps all interaction evidence onto a common set of genomes and proteins. The most important new developments in STRING 8 over previous releases include a URL-based…
Citation impact
- FWCI
- 82.68
- Percentile
- 100%
- References
- 35
Authors
12Topics & keywords
- String (physics)
- Biology
- Computational biology
- Annotation
- Genome
- Protein–protein interaction
- Set (abstract data type)
- Computer science
- Partnerships for the goals