Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients
Heidelberg University · Charité - Universitätsmedizin Berlin · +29 more institutions
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Abstract
Background
The diagnostic and pathophysiological relevance of antibodies to aquaporin-4 (AQP4-Ab) in patients with neuromyelitis optica spectrum disorders (NMOSD) has been intensively studied. However, little is known so far about the clinical impact of AQP4-Ab seropositivity.
Objective
To analyse systematically the clinical and paraclinical features associated with NMO spectrum disorders in Caucasians in a stratified fashion according to the patients' AQP4-Ab serostatus.
Citation impact
760
total citations
- FWCI
- 33.51
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- 100%
- References
- 81
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Authors
49Topics & keywords
Topics
Keywords
- Medicine
- Neuromyelitis optica
- Myelitis
- Serostatus
- Optic neuritis
- Internal medicine
- Neurology
- Spinal cord
UN Sustainable Development Goals
- Good health and well-being
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