articleJournal of Clinical OncologyJul 6, 2005BRONZE OA

Phase II Trial of Temsirolimus (CCI-779) in Recurrent Glioblastoma Multiforme: A North Central Cancer Treatment Group Study

The University of Texas at San Antonio Health Science Center · North Central Cancer Treatment Group

PubMed
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Abstract

Background

Temsirolimus (CCI-779) is a small-molecule inhibitor of the mammalian target of rapamycin (mTOR) and represents a rational therapeutic target against glioblastoma multiforme (GBM).

Methods

Recurrent GBM patients with

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