Multiplexed Echo Planar Imaging for Sub-Second Whole Brain FMRI and Fast Diffusion Imaging
Advanced MRI Technologies (United States) · University of California, San Francisco · +7 more institutions
Abstract
Echo planar imaging (EPI) is an MRI technique of particular value to neuroscience, with its use for virtually all functional MRI (fMRI) and diffusion imaging of fiber connections in the human brain. EPI generates a single 2D image in a fraction of a second; however, it requires 2-3 seconds to acquire multi-slice whole brain coverage for fMRI and even longer for diffusion imaging. Here we report on a large reduction in EPI whole brain scan time at 3 and 7 Tesla, without significantly sacrificing spatial resolution, and while gaining functional sensitivity. The multiplexed-EPI (M-EPI) pulse sequence combines two forms of multiplexing: temporal multiplexing (m) utilizing simultaneous echo refocused (SIR) EPI and…
Citation impact
- FWCI
- 44.93
- Percentile
- 100%
- References
- 58
Authors
9- DADavid A. FeinbergCorresponding
Advanced MRI Technologies (United States), University of California, San Francisco, University of California, Berkeley
- SMSteen Moeller
University of Minnesota, Resonance Research (United States)
- SMStephen M. Smith
University of Oxford, John Radcliffe Hospital, Wellcome Centre for Integrative Neuroimaging
- EJEdward J. Auerbach
Resonance Research (United States), University of Minnesota
- SRSudhir Ramanna
Topics & keywords
- Functional magnetic resonance imaging
- Echo-planar imaging
- Diffusion imaging
- Physics
- Multiplexing
- Diffusion MRI
- Nuclear magnetic resonance
- Magnetic resonance imaging