COMPARTMENTS: unification and visualization of protein subcellular localization evidence
University of Luxembourg · Novo Nordisk Foundation · +2 more institutions
Abstract
Information on protein subcellular localization is important to understand the cellular functions of proteins. Currently, such information is manually curated from the literature, obtained from high-throughput microscopy-based screens and predicted from primary sequence. To get a comprehensive view of the localization of a protein, it is thus necessary to consult multiple databases and prediction tools. To address this, we present the COMPARTMENTS resource, which integrates all sources listed above as well as the results of automatic text mining. The resource is automatically kept up to date with source databases, and all localization evidence is mapped onto common protein identifiers and Gene Ontology terms.…
Citation impact
- FWCI
- 11.81
- Percentile
- 100%
- References
- 53
Authors
7- JXJanos X. BinderCorresponding
University of Luxembourg
- SPSune Pletscher-Frankild
Novo Nordisk Foundation, European Molecular Biology Laboratory, Garvan Institute of Medical Research, University of Luxembourg
- KTKalliopi Tsafou
University of Luxembourg, European Molecular Biology Laboratory, Novo Nordisk Foundation, Garvan Institute of Medical Research
- CSChristian Stolte
University of Luxembourg, European Molecular Biology Laboratory, Garvan Institute of Medical Research, Novo Nordisk Foundation
- SOSéan O’Donoghue
Garvan Institute of Medical Research, Novo Nordisk Foundation, European Molecular Biology Laboratory, University of Luxembourg
Topics & keywords
- Unification
- Visualization
- Computer science
- Subcellular localization
- Computational biology
- Information retrieval
- Artificial intelligence
- Cell biology