The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease
St Vincent's Hospital · Mental Health Research Institute · +10 more institutions
Abstract
The Australian Imaging, Biomarkers and Lifestyle (AIBL) flagship study of aging aimed to recruit 1000 individuals aged over 60 to assist with prospective research into Alzheimer's disease (AD). This paper describes the recruitment of the cohort and gives information about the study methodology, baseline demography, diagnoses, medical comorbidities, medication use, and cognitive function of the participants.
Volunteers underwent a screening interview, had comprehensive cognitive testing, gave 80 ml of blood, and completed health and lifestyle questionnaires. One quarter of the sample also underwent amyloid PET brain imaging with Pittsburgh compound B (PiB PET) and MRI brain imaging, and a subgroup of 10% had ActiGraph activity monitoring and body composition scanning.
Citation impact
- FWCI
- 12.70
- Percentile
- 100%
- References
- 47
Authors
20- KAKathryn A. EllisCorresponding
St Vincent's Hospital, Mental Health Research Institute, University of Melbourne, National Ageing Research Institute
- AIAshley I. Bush
University of Melbourne, Mental Health Research Institute
- DDDavid Darby
University of Melbourne
- DDDaniela De Fazio
Mental Health Research Institute, University of Melbourne
- JKJonathan K. Foster
Edith Cowan University, Hollywood Private Hospital, Government of Western Australia Department of Health
Topics & keywords
- Cohort
- Dementia
- Neuropsychology
- Cognition
- Medicine
- Cognitive decline
- Gerontology
- Cohort study