Uberon, an integrative multi-species anatomy ontology
Lawrence Berkeley National Laboratory · Oregon Health & Science University · +1 more institution
Abstract
We present Uberon, an integrated cross-species ontology consisting of over 6,500 classes representing a variety of anatomical entities, organized according to traditional anatomical classification criteria. The ontology represents structures in a species-neutral way and includes extensive associations to existing species-centric anatomical ontologies, allowing integration of model organism and human data. Uberon provides a necessary bridge between anatomical structures in different taxa for cross-species inference. It uses novel methods for representing taxonomic variation, and has proved to be essential for translational phenotype analyses. Uberon is available at http://uberon.org.
Citation impact
- FWCI
- 18.41
- Percentile
- 100%
- References
- 67
Authors
5Topics & keywords
- Biology
- Evolutionary biology
- Ontology
- Human genetics
- Genome Biology
- Gene ontology
- Computational biology
- Genomics
- Life in Land
Funding
- UDU.S. Department of EnergyAwards: -AC02-05CH11231, 05CH11231, AC02-05CH11231, DE-AC02, DE-AC02-05CH11231, DE-AC02-
- NINational Institutes of HealthAward: DE-AC02-05CH11231
- OOOffice of ScienceAwards: AC02-05CH11231, -AC02-05CH11231, DE-AC02
- BEBasic Energy SciencesAwards: DE-AC02, AC02-05CH11231, DE-AC02-05CH11231, -AC02-05CH11231