Fluorine in medicinal chemistry
Oxford Research Group · Mansfield University · +1 more institution
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Abstract
It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.
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7,392
total citations
- FWCI
- 51.84
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- 100%
- References
- 129
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Authors
4Topics & keywords
Topics
Keywords
- Fluorine
- Chemistry
- Combinatorial chemistry
- Organic chemistry
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