Resazurin Microtiter Assay Plate: Simple and Inexpensive Method for Detection of Drug Resistance in Mycobacterium tuberculosis
Instituut voor Tropische Geneeskunde · Universidad Peruana Cayetano Heredia · +1 more institution
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Abstract
A method for detecting multidrug-resistant Mycobacterium tuberculosis by using a reduction of resazurin is described. Eighty clinical isolates were evaluated against isoniazid and rifampin; results at 7 days were compared with those of the proportion method. Specificity and sensitivity were excellent. The method is simple, inexpensive, and rapid and might be used with other antituberculosis drugs.
Citation impact
1,211
total citations
- FWCI
- 2.90
- Percentile
- 100%
- References
- 42
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Authors
6Topics & keywords
Topics
Keywords
- Resazurin
- Microtiter plate
- Mycobacterium tuberculosis
- Drug resistance
- Microbiology
- Tuberculosis
- Mycobacterium
- Biology
UN Sustainable Development Goals
- Good health and well-being
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