letterNatureNov 1, 2004Closed access

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

JSJürgen SoutschekAAAkin AkincBBBirgit BramlageKCKlaus CharisséRCRainer Constien

ALK-Abelló (Germany) · Alnylam Pharmaceuticals (United States)

PubMed
Indexed incrossrefpubmed

Abstract

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Authors

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Topics & keywords

Topics
Keywords
  • Small interfering RNA
  • Gene silencing
  • RNA interference
  • RNA silencing
  • Systemic administration
  • Apolipoprotein B
  • Biology
  • Cell biology
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