Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome
Centers for Disease Control and Prevention · University of California, San Francisco · +3 more institutions
Abstract
In March 2003, a novel coronavirus (SARS-CoV) was discovered in association with cases of severe acute respiratory syndrome (SARS). The sequence of the complete genome of SARS-CoV was determined, and the initial characterization of the viral genome is presented in this report. The genome of SARS-CoV is 29,727 nucleotides in length and has 11 open reading frames, and its genome organization is similar to that of other coronaviruses. Phylogenetic analyses and sequence comparisons showed that SARS-CoV is not closely related to any of the previously characterized coronaviruses.
Citation impact
- FWCI
- 388.86
- Percentile
- 100%
- References
- 15
Authors
35- PAPaul A. RotaCorresponding
Centers for Disease Control and Prevention, University of California, San Francisco, National Center for Infectious Diseases, Erasmus University Rotterdam, Bernhard Nocht Institute for Tropical Medicine
- MSM. Steven Oberste
Centers for Disease Control and Prevention, University of California, San Francisco, National Center for Infectious Diseases, Erasmus University Rotterdam, Bernhard Nocht Institute for Tropical Medicine
- SSStephan S. Monroe
Centers for Disease Control and Prevention, University of California, San Francisco, National Center for Infectious Diseases, Erasmus University Rotterdam, Bernhard Nocht Institute for Tropical Medicine
- WAW. Allan Nix
Centers for Disease Control and Prevention, University of California, San Francisco, National Center for Infectious Diseases, Erasmus University Rotterdam, Bernhard Nocht Institute for Tropical Medicine
- RPRaymond P. Campagnoli
Centers for Disease Control and Prevention, University of California, San Francisco, National Center for Infectious Diseases, Erasmus University Rotterdam, Bernhard Nocht Institute for Tropical Medicine
Topics & keywords
- Coronavirus disease 2019 (COVID-19)
- Coronavirus
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- 2019-20 coronavirus outbreak
- Betacoronavirus
- Respiratory system
- Medicine
- Severe acute respiratory syndrome
- Good health and well-being