Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis

Roy, Aditya; Eisenhut, Michael; Harris, Ross; Rodrigues, Laura C.; Sridhar, Saranya; Habermann, Stephanie; Snell, Luke B.; Mangtani, Punam; Adetifa, Ifedayo; Lalvani, Ajit; Abubakar, Ibrahim

doi:10.1136/bmj.g4643

reviewBMJAug 5, 2014HYBRID OA

Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis

ARAditya Roy MEMichael Eisenhut RHRoss Harris LCLaura C. Rodrigues SSSaranya Sridhar

Public Health England · Luton and Dunstable University Hospital NHS Foundation Trust · +5 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

Objectives

To determine whether BCG vaccination protects against Mycobacterium tuberculosis infection as assessed by interferon γ release assays (IGRA) in children.

Design

Systematic review and meta-analysis. Searches of electronic databases 1950 to November 2013, checking of reference lists, hand searching of journals, and contact with experts.

Citation impact

583

total citations

FWCI: 26.87
Percentile: 100%
References: 36

Citations per year

Authors

11

Topics & keywords

Topics

Keywords

Medicine
Tuberculosis
QuantiFERON
Vaccination
Mycobacterium tuberculosis
ELISPOT
Meta-analysis
Immunology

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