articleJournal of NeuroscienceFeb 28, 2007BRONZE OA

Dissociable Intrinsic Connectivity Networks for Salience Processing and Executive Control

University of California, San Francisco · Stanford University

PubMed
Indexed incrossrefpubmed

Abstract

Variations in neural circuitry, inherited or acquired, may underlie important individual differences in thought, feeling, and action patterns. Here, we used task-free connectivity analyses to isolate and characterize two distinct networks typically coactivated during functional MRI tasks. We identified a "salience network," anchored by dorsal anterior cingulate (dACC) and orbital frontoinsular cortices with robust connectivity to subcortical and limbic structures, and an "executive-control network" that links dorsolateral frontal and parietal neocortices. These intrinsic connectivity networks showed dissociable correlations with functions measured outside the scanner. Prescan anxiety ratings correlated with…

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Authors

8

Topics & keywords

Keywords
  • Psychology
  • Task-positive network
  • Salience (neuroscience)
  • Neuroscience
  • Anterior cingulate cortex
  • Functional connectivity
  • Default mode network
  • Cognitive psychology
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