Inflammation, Immunity, and Hypertension
Jagiellonian University · Stanford University
Abstract
Aprominent pathology textbook used in the United States includes an image illustrating the renal histopathology caused by malignant hypertension. The legend describes striking “onion skin” changes of a renal arteriole. Curiously, a sea of mononuclear inflammatory cells surrounding this arteriole is overlooked both in the legend and in the related text. Moreover, nothing regarding inflammation or immune reactions is discussed. This lack of attention to inflammatory cells is, however, not surprising. Although many experimental studies have implicated inflammation in hypertension, these have largely been performed in experimental animals; there is no proof that inflammation contributes to human hypertension. In…
Citation impact
- FWCI
- 32.68
- Percentile
- 100%
- References
- 96
Authors
8- DGDavid G. HarrisonCorresponding
Jagiellonian University, Stanford University
- TJTomasz J. Guzik
Stanford University, Jagiellonian University
- HEHeinrich E. Lob
Jagiellonian University, Stanford University
- MSMeena S. Madhur
Jagiellonian University, Stanford University
- PJPaul J. Marvar
Stanford University, Jagiellonian University
Topics & keywords
- Inflammation
- Immunity
- Medicine
- Immunology
- Immune system