A Review of Methods for Correction of Intensity Inhomogeneity in MRI

Medical image acquisition devices provide a vast amount of anatomical and functional information, which facilitate and improve diagnosis and patient treatment, especially when supported by modern quantitative image analysis methods. However, modality specific image artifacts, such as the phenomena of intensity inhomogeneity in magnetic resonance images (MRI), are still prominent and can adversely affect quantitative image analysis. In this paper, numerous methods that have been developed to reduce or eliminate intensity inhomogeneities in MRI are reviewed. First, the methods are classified according to the inhomogeneity correction strategy. Next, different qualitative and quantitative evaluation approaches are…