Persistent immune activation in HIV-1 infection is associated with progression to AIDS
Sanquin · Karl Landsteiner Society · +1 more institution
Indexed incrossrefpubmed
Abstract
Background
HIV-1 infection is characterized by chronic generalized CD8 and CD4 T cell hyperactivation, the biological effect of which is not understood.
Objective
To study the relation between chronic immune activation and CD4 T cell depletion in HIV-1 infection.
Citation impact
779
total citations
- FWCI
- 9.25
- Percentile
- 100%
- References
- 31
Citations per year
Authors
9Topics & keywords
Topics
Keywords
- Immunology
- Human immunodeficiency virus (HIV)
- Immunopathology
- Immune system
- Medicine
- Virology
- Viral disease
- Sida
UN Sustainable Development Goals
- Good health and well-being
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