articleThe American Journal of GastroenterologyApr 14, 2015Closed access

ACG Clinical Guideline: Primary Sclerosing Cholangitis

Mayo Clinic in Florida · WinnMed · +2 more institutions

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Abstract

Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver transplantation. The cause is unknown, although it is commonly associated with colitis. There is no approved or proven therapy, although ursodeoxycholic acid is used by many on an empiric basis. Complications including portal hypertension, fat-soluble vitamin deficiency, metabolic bone diseases, and development of cancers of the bile duct or colon can occur.

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Authors

3

Topics & keywords

Keywords
  • Medicine
  • Primary sclerosing cholangitis
  • Ursodeoxycholic acid
  • Gastroenterology
  • Liver transplantation
  • Guideline
  • Internal medicine
  • Portal hypertension
UN Sustainable Development Goals
  • Good health and well-being
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