articleBMC BioinformaticsFeb 23, 2006GOLD OA

SIMMAP: Stochastic character mapping of discrete traits on phylogenies

University of Copenhagen

PubMed
Indexed incrossrefdoajpubmed

Abstract

Background

Character mapping on phylogenies has played an important, if not critical role, in our understanding of molecular, morphological, and behavioral evolution. Until very recently we have relied on parsimony to infer character changes. Parsimony has a number of serious limitations that are drawbacks to our understanding. Recent statistical methods have been developed that free us from these limitations enabling us to overcome the problems of parsimony by accommodating uncertainty in evolutionary time, ancestral states, and the phylogeny.

Results

SIMMAP has been developed to implement stochastic character mapping that is useful to both molecular evolutionists, systematists, and bioinformaticians. Researchers can address questions about positive selection, patterns of amino acid substitution, character association, and patterns of morphological evolution.

Citation impact

961
total citations
FWCI
9.95
Percentile
100%
References
40
Citations per year

Authors

1

Topics & keywords

Keywords
  • Character (mathematics)
  • Character evolution
  • Bayesian probability
  • Substitution (logic)
  • Phylogenetics
  • Maximum parsimony
  • Biology
  • Probabilistic logic
No related works found for this paper.

Funding