Microscale technologies for tissue engineering and biology
Brigham and Women's Hospital · Harvard University · +4 more institutions
Abstract
Microscale technologies are emerging as powerful tools for tissue engineering and biological studies. In this review, we present an overview of these technologies in various tissue engineering applications, such as for fabricating 3D microfabricated scaffolds, as templates for cell aggregate formation, or for fabricating materials in a spatially regulated manner. In addition, we give examples of the use of microscale technologies for controlling the cellular microenvironment in vitro and for performing high-throughput assays. The use of microfluidics, surface patterning, and patterned cocultures in regulating various aspects of cellular microenvironment is discussed, as well as the application of these…
Citation impact
- FWCI
- 89.39
- Percentile
- 100%
- References
- 115
Authors
4- AKAli KhademhosseiniCorresponding
Brigham and Women's Hospital, Harvard University, Harvard–MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology
- RLRóbert Langer
Harvard–MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology
- JTJeffrey T. Borenstein
Draper Laboratory
- JPJoseph P. Vacanti
Harvard University, Massachusetts General Hospital
Topics & keywords
- Microscale chemistry
- Microfluidics
- Nanotechnology
- Tissue engineering
- Synthetic biology
- Computer science
- Emerging technologies
- Biochemical engineering