Effect of Antihypertensive Agents on Cardiovascular Events in Patients With Coronary Disease and Normal Blood Pressure

Nissen, Steven E.; Tuzcu, E. Murat; Libby, Peter; Thompson, Paul D.; Ghali, Magdi; Garza, Dahlia; Berman, Lance; Shi, Harry; Buebendorf, Ethel; Topol, Eric J.; Investigators, for the CAMELOT

doi:10.1001/jama.292.18.2217

articleJAMANov 9, 2004Closed access

Effect of Antihypertensive Agents on Cardiovascular Events in Patients With Coronary Disease and Normal Blood Pressure

SESteven E. Nissen EME. Murat Tuzcu PLPeter LibbyPDPaul D. ThompsonMGMagdi Ghali

Cleveland Clinic · Cleveland Clinic Lerner College of Medicine · +4 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

CONTEXT: The effect of antihypertensive drugs on cardiovascular events in patients with coronary artery disease (CAD) and normal blood pressure remains uncertain. OBJECTIVE: To compare the effects of amlodipine or enalapril vs placebo on cardiovascular events in patients with CAD. DESIGN, SETTING, AND PARTICIPANTS: Double-blind, randomized, multicenter, 24-month trial (enrollment April 1999-April 2002) comparing amlodipine or enalapril with placebo in 1991 patients with angiographically documented CAD (>20% stenosis by coronary angiography) and diastolic blood pressure

Citation impact

1,154

total citations

FWCI: 53.20
Percentile: 100%
References: 24

Citations per year

Authors

11

SE
Steven E. NissenCorresponding
Cleveland Clinic, Cleveland Clinic Lerner College of Medicine
EM
E. Murat Tuzcu
Cleveland Clinic
PL
Peter Libby
Pfizer (United States), Harvard University Press
PD
Paul D. Thompson
Hartford Hospital
MG
Magdi Ghali
Iowa Orthopaedic Center

Topics & keywords

Topics

Keywords

Medicine
Amlodipine
Enalapril
Cardiology
Internal medicine
Blood pressure
Myocardial infarction
Placebo

UN Sustainable Development Goals

Good health and well-being

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