Metagenomics - a guide from sampling to data analysis
UNSW Sydney · Argonne National Laboratory · +1 more institution
Abstract
Metagenomics applies a suite of genomic technologies and bioinformatics tools to directly access the genetic content of entire communities of organisms. The field of metagenomics has been responsible for substantial advances in microbial ecology, evolution, and diversity over the past 5 to 10 years, and many research laboratories are actively engaged in it now. With the growing numbers of activities also comes a plethora of methodological knowledge and expertise that should guide future developments in the field. This review summarizes the current opinions in metagenomics, and provides practical guidance and advice on sample processing, sequencing technology, assembly, binning, annotation, experimental design,…
Citation impact
- FWCI
- 26.20
- Percentile
- 100%
- References
- 98
Authors
3Topics & keywords
- Metagenomics
- Data science
- Suite
- Field (mathematics)
- Computer science
- Annotation
- Data sharing
- Sample (material)
Funding
- UDU.S. Department of EnergyAwards: AC02-06CH11357, Contract No. DE-AC02-06CH11357, DE-AC02, 06CH11357, No. DE-AC02-06CH11357, DE-AC02-06CH11357, DE-AC02-
- UOUniversity of ChicagoAward: DE-AC02-06CH11357
- OOOffice of ScienceAwards: DE-AC02-06CH11357, Contract No. DE-AC02-06CH11357, DE-AC02, No. DE-AC02-06CH11357, 06CH11357, AC02-06CH11357
- ARAustralian Research Council
- ANArgonne National LaboratoryAwards: DE-AC02, Contract DE-AC02-06CH11357, No. DE-AC02-06CH11357, 06CH11357, AC02-06CH11357, Contract No. DE-AC02-06CH11357