article·Cell·Oct 24, 2014BRONZE OA

Toehold Switches: De-Novo-Designed Regulators of Gene Expression

AAAlexander A. GreenPAPamela A. SilverJJJames J. CollinsPYPeng YinCorresponding author

Harvard University · Center for Systems Biology · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

832
total citations
FWCI
23.19
Percentile
100%
References
57
Citations per year

Authors

4
  • AA
    Alexander A. Green

    Harvard University

  • PA
    Pamela A. Silver

    Harvard University, Center for Systems Biology

  • JJ
    James J. Collins

    Boston University, Howard Hughes Medical Institute, Harvard University

  • PY
    Peng YinCorresponding

    Harvard University, Center for Systems Biology

Topics & keywords

Topics
  • Primary topicRNA and protein synthesis mechanisms100%
  • CRISPR and Genetic Engineering100%
  • Advanced biosensing and bioanalysis techniques100%
Keywords
  • Biology
  • Synthetic biology
  • Crosstalk
  • Computational biology
  • Orthogonality
  • Gene
  • Gene regulatory network
  • Exploit
No related works found for this paper.

Funding

  • NS
    National Science Foundation
  • HH
    Howard Hughes Medical Institute
  • NI
    National Institutes of Health
  • DA
    Defense Advanced Research Projects Agency
  • DT
    Defense Threat Reduction Agency
  • MU
    Multidisciplinary University Research Initiative
  • HW
    Hansjörg Wyss Institute for Biologically Inspired Engineering, Harvard University
  • OO
    Office of Naval Research