Hermaphroditic, demasculinized frogs after exposure to the herbicide atrazine at low ecologically relevant doses
Museum of Vertebrate Zoology · University of California, Berkeley
Abstract
Atrazine is the most commonly used herbicide in the U.S. and probably the world. It can be present at several parts per million in agricultural runoff and can reach 40 parts per billion (ppb) in precipitation. We examined the effects of atrazine on sexual development in African clawed frogs (Xenopus laevis). Larvae were exposed to atrazine (0.01-200 ppb) by immersion throughout larval development, and we examined gonadal histology and laryngeal size at metamorphosis. Atrazine (> or =0.1 ppb) induced hermaphroditism and demasculinized the larynges of exposed males (> or =1.0 ppb). In addition, we examined plasma testosterone levels in sexually mature males. Male X. laevis suffered a 10-fold decrease in…
Citation impact
- FWCI
- 57.26
- Percentile
- 100%
- References
- 53
Authors
7- TBTyrone B. HayesCorresponding
Museum of Vertebrate Zoology, University of California, Berkeley
- ACAtif Collins
Museum of Vertebrate Zoology, University of California, Berkeley
- MLMelissa Lee
Museum of Vertebrate Zoology, University of California, Berkeley
- MAM. A. Mendoza
Museum of Vertebrate Zoology, University of California, Berkeley
- NNNigel Noriega
Museum of Vertebrate Zoology, University of California, Berkeley
Topics & keywords
- Atrazine
- Amphibian
- Biology
- Endocrine disruptor
- Xenopus
- Endocrine system
- Testosterone (patch)
- Larva