Predictive Value of Brachial Flow-Mediated Dilation for Incident Cardiovascular Events in a Population-Based Study
University of Minnesota · Johns Hopkins University · +5 more institutions
Abstract
BACKGROUND: Although brachial artery flow-mediated dilation (FMD) predicts recurrent cardiovascular events, its predictive value for incident cardiovascular disease (CVD) events in adults free of CVD is not well established. We assessed the predictive value of FMD for incident CVD events in the Multi-Ethnic Study of Atherosclerosis (MESA). METHODS AND RESULTS: Brachial artery FMD was measured in a nested case-cohort sample of 3026 of 6814 subjects (mean+/-SD age, 61.2+/-9.9 years) in MESA, a population-based cohort study of adults free of clinical CVD at baseline recruited at 6 clinic sites in the United States. The sample included 50.2% female, 34.3% white, 19.7% Chinese, 20.8% black, and 25.1% Hispanic…
Citation impact
- FWCI
- 37.96
- Percentile
- 100%
- References
- 27
Authors
9- JYJoseph YeboahCorresponding
University of Minnesota, Johns Hopkins University, University of Washington, Johns Hopkins Medicine, The Coordinating Center, Wake Forest University, University of Virginia
- ARAaron R. Folsom
University of Minnesota, Johns Hopkins University, University of Washington, Johns Hopkins Medicine, The Coordinating Center, Wake Forest University, University of Virginia
- GLGregory L. Burke
University of Minnesota, Johns Hopkins University, University of Washington, Johns Hopkins Medicine, The Coordinating Center, Wake Forest University, University of Virginia
- CJCraig Johnson
University of Minnesota, Johns Hopkins University, University of Washington, Johns Hopkins Medicine, The Coordinating Center, Wake Forest University, University of Virginia
- JFJoseph F. Polak
University of Minnesota, Johns Hopkins University, University of Washington, Johns Hopkins Medicine, The Coordinating Center, Wake Forest University, University of Virginia
Topics & keywords
- Medicine
- Hazard ratio
- Internal medicine
- Cardiology
- Myocardial infarction
- Proportional hazards model
- Confidence interval
- Population
- Good health and well-being