Effect of Allopurinol in Chronic Kidney Disease Progression and Cardiovascular Risk

Goicoechea, Marián; Vinuesa, Soledad García de; Verdalles, Úrsula; Ruiz-Caro, Caridad; Ampuero, Jara; Rincón, Abraham; Arroyo, David; Luño, José

doi:10.2215/cjn.01580210

articleClinical Journal of the American Society of NephrologyJun 10, 2010GREEN OA

Effect of Allopurinol in Chronic Kidney Disease Progression and Cardiovascular Risk

MGMarián Goicoechea SGSoledad García de Vinuesa ÚVÚrsula Verdalles CRCaridad Ruiz-Caro JAJara Ampuero

Hospital General Universitario Gregorio Marañón

PubMed

Indexed incrossrefpubmed

Abstract

BACKGROUND AND OBJECTIVES: Hyperuricemia is associated with hypertension, inflammation, renal disease progression, and cardiovascular disease. However, no data are available regarding the effect of allopurinol in patients with chronic kidney disease. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a prospective, randomized trial of 113 patients with estimated GFR (eGFR)

Citation impact

827

total citations

FWCI: 32.07
Percentile: 100%
References: 20

Citations per year

Authors

8

Topics & keywords

Topics

Keywords

Medicine
Allopurinol
Kidney disease
Internal medicine
Hyperuricemia
Diabetes mellitus
C-reactive protein
Albuminuria

UN Sustainable Development Goals

Good health and well-being

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