The physiology of climate change: how potentials for acclimatization and genetic adaptation will determine ‘winners’ and ‘losers’

Physiological studies can help predict effects of climate change through determining which species currently live closest to their upper thermal tolerance limits, which physiological systems set these limits, and how species differ in acclimatization capacities for modifying their thermal tolerances. Reductionist studies at the molecular level can contribute to this analysis by revealing how much change in sequence is needed to adapt proteins to warmer temperatures--thus providing insights into potential rates of adaptive evolution--and determining how the contents of genomes--protein-coding genes and gene regulatory mechanisms--influence capacities for adapting to acute and long-term increases in temperature.…

• NS
  National Science Foundation
• DA
  David and Lucile Packard Foundation
• GA
  Gordon and Betty Moore Foundation