Brain Maturation in Adolescence and Young Adulthood: Regional Age-Related Changes in Cortical Thickness and White Matter Volume and Microstructure

Tamnes, Christian K.; Østby, Ylva; Fjell, Anders M.; Westlye, Lars T.; Due‐Tønnessen, Paulina; Walhovd, Kristine B.

doi:10.1093/cercor/bhp118

articleCerebral CortexJun 11, 2009BRONZE OA

Brain Maturation in Adolescence and Young Adulthood: Regional Age-Related Changes in Cortical Thickness and White Matter Volume and Microstructure

CKChristian K. Tamnes YØYlva Østby AMAnders M. Fjell LTLars T. Westlye PDPaulina Due‐Tønnessen

University of Oslo · Oslo University Hospital

PubMed

Indexed incrossrefpubmed

Abstract

The development of cortical gray matter, white matter (WM) volume, and WM microstructure in adolescence is beginning to be fairly well characterized by structural magnetic resonance imaging (sMRI) and diffusion tensor imaging (DTI) studies. However, these aspects of brain development have rarely been investigated concurrently in the same sample and hence the relations between them are not understood. We delineated the age-related changes in cortical thickness, regional WM volume, and diffusion characteristics and investigated the relationships between these properties of brain development. One hundred and sixty-eight healthy participants aged 8-30 years underwent sMRI and DTI. The results showed regional…

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Topics & keywords

Topics

Keywords

White matter
Diffusion MRI
Psychology
Magnetic resonance imaging
Brain size
Neuroscience
Brain development
Medicine

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