articleNature CommunicationsApr 23, 2015GOLD OA

Structural reducibility of multilayer networks

MDManlio De DomenicoVNVincenzo NicosiaÀAÀlex ArenasVLVito Latora

Universitat Rovira i Virgili · Queen Mary University of London · +2 more institutions

PubMed
Indexed inarxivcrossrefdoajpubmed

Abstract

Many complex systems can be represented as networks consisting of distinct types of interactions, which can be categorized as links belonging to different layers. For example, a good description of the full protein–protein interactome requires, for some organisms, up to seven distinct network layers, accounting for different genetic and physical interactions, each containing thousands of protein–protein relationships. A fundamental open question is then how many layers are indeed necessary to accurately represent the structure of a multilayered complex system. Here we introduce a method based on quantum theory to reduce the number of layers to a minimum while maximizing the distinguishability between the…

Citation impact

647
total citations
FWCI
43.13
Percentile
100%
References
54
Citations per year

Authors

4

Topics & keywords

Topics
Keywords
  • Interactome
  • Computer science
  • Graph
  • Theoretical computer science
  • Biological network
  • Complex system
  • Quantum
  • Complex network
No related works found for this paper.

Funding