articleMolecular Biology and EvolutionApr 16, 2014GREEN OA

PopGenome: An Efficient Swiss Army Knife for Population Genomic Analyses in R

Heinrich Heine University Düsseldorf · Center for Research in Agricultural Genomics

PubMed
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Abstract

Although many computer programs can perform population genetics calculations, they are typically limited in the analyses and data input formats they offer; few applications can process the large data sets produced by whole-genome resequencing projects. Furthermore, there is no coherent framework for the easy integration of new statistics into existing pipelines, hindering the development and application of new population genetics and genomics approaches. Here, we present PopGenome, a population genomics package for the R software environment (a de facto standard for statistical analyses). PopGenome can efficiently process genome-scale data as well as large sets of individual loci. It reads DNA alignments and…

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Topics & keywords

Keywords
  • International HapMap Project
  • Linkage disequilibrium
  • Biology
  • Population
  • Coalescent theory
  • 1000 Genomes Project
  • Population genomics
  • Genomics
UN Sustainable Development Goals
  • Partnerships for the goals
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