Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new onset epilepsy [RETIRED]
Harvard University · Cornell University · +4 more institutions
Abstract
To assess the evidence demonstrating efficacy, tolerability, and safety of seven new antiepileptic drugs (AEDs) (gabapentin, lamotrigine, topiramate, tiagabine, oxcarbazepine, levetiracetam, and zonisamide-reviewed in the order in which these agents received approval by the US Food and Drug Administration) in the treatment of children and adults with newly diagnosed partial and generalized epilepsies.
A 23-member committee, including general neurologists, pediatric neurologists, epileptologists, and doctors in pharmacy, evaluated the available evidence based on a structured literature review including MEDLINE, Current Contents, and Cochrane library for relevant articles from 1987 until September 2002, with selected manual searches up until 2003.
Citation impact
- FWCI
- 28.04
- Percentile
- 100%
- References
- 117
Authors
24- JAJacqueline A. FrenchCorresponding
Harvard University, Cornell University, Beth Israel Deaconess Medical Center, University Medical Center, University of Illinois Chicago, Boston University
- AMAndrés M. Kanner
Boston University, University Medical Center, Beth Israel Deaconess Medical Center, Harvard University, University of Illinois Chicago, Cornell University
- JFJocelyn F. Bautista
Beth Israel Deaconess Medical Center, University of Illinois Chicago, University Medical Center, Cornell University, Boston University, Harvard University
- BAB. Abou‐Khalil
Cornell University, Harvard University, Boston University, Beth Israel Deaconess Medical Center, University Medical Center, University of Illinois Chicago
- TBThomas Browne
Harvard University, Cornell University, University Medical Center, University of Illinois Chicago, Boston University, Beth Israel Deaconess Medical Center
Topics & keywords
- Oxcarbazepine
- Lamotrigine
- Topiramate
- Medicine
- Gabapentin
- Tolerability
- Levetiracetam
- Zonisamide
- Good health and well-being